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Description
M-CSFR His Tag Protein, HumanProduct Specification Species Human Synonyms M CSFR, CD115, FIM2, FMS, CSF1R Accession P07333 Amino Acid Sequence Ile20 Glu512, with C 8*His Expression System HEK293 Molecular Weight 75 90kDa Purity >95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4 Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in ultrapure water after rapid centrifugation.
Product Specification
| Species | Human |
| Synonyms | M-CSFR, CD115, FIM2, FMS, CSF1R |
| Accession | P07333 |
| Amino Acid Sequence | Ile20-Glu512, with C-8*His |
| Expression System | HEK293 |
| Molecular Weight | 75-90kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference |
1、Sapi E. et al. (1999) The role of CSF-1 in normal and neoplastic breast physiology. Proc Soc Exp Biol Med. 220(1): 1-8. 2、Sapi E. (2004) The role of CSF-1 in normal physiology of mammary gland and breast cancer: an update. Exp Biol Med (Maywood). 229(1): 1-11. 3、Bonifer C. et al. (2008) The transcriptional regulation of the Colony-Stimulating Factor 1 Receptor (csf1r) gene during hematopoiesis. Front Biosci. 13: 549-560. |
Background
Colony stimulating factor 1 receptor (CSF1R) is also known as macrophage colony-stimulating factor receptor (M-CSFR), CD115 Cluster of Differentiation 115 (CD115), C-FMS, CSFR, FIM2, FMS, and is a member of the type Ⅲ subfamily of receptor tyrosine kinases. M-CSF receptor, the product of the c-fms proto-oncogene, is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each contain five immunoglobulin-like domains in their extracellular domain (ECD) and a split kinase domain in their intracellular region. M-CSF receptor is expressed primarily on cells of the monocyte/macrophage lineage, dendritic cells, stem cells and in the developing placenta. M-CSF R engagement is continuously required for macrophage survival and regulates lineage decisions and maturation of monocytes, macrophages, osteoclasts and DC. M-CSF R and integrin alpha v beta 3 share signaling pathways during osteoclastogenesis and deletion of either causes osteopetrosis. In the brain, microglia expressing increased M-CSF R are concentrated with Alzheimers a beta peptide, but their role in pathogenesis is unclear.
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Exchange/Return Notes
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4.0 ★★★★★
Based on 20 reviews
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Product Reviews
★★★★★ 5
This Rotating Jewelry Box Is a Game-Changer for Organizing Your Collection
This jewelry box is a total winner for anyone who loves to keep their accessories beautifully displayed yet perfectly organized. The design is elegant and modern, with a clean cream finish, gold-tone handle, and a clear panel that gives it a sophisticated, boutique-style look.
It’s thoughtfully structured with specific compartments for everything — earrings, necklaces, rings, watches, and even a top tray that’s ideal for everyday pieces you reach for the most. The built-in mirror adds a functional touch, making it easy to put on jewelry without having to move to another room. But the real showstopper? The entire box rotates smoothly, giving you 360° access to your collection — stylish and practical.
This piece doesn’t just store jewelry; it elevates your space. Perfect for anyone who wants a beautiful and functional way to organize their treasures without clutter.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on October 20, 2025
★★★★★ 5
Easy access from the wonderful design
I love this jewelry box!!! It holds sooo much and everything is easy and convenient to access with the spinning design!
Functioning: The designated hooks for necklaces keep them from getting tangled. The slide out drawers are easy to pull and I love that it has space specifically for bracelets or watches! I am thrilled with the holes to keep earrings together and pairs easy to grab, dangling or hoops work well on in the side area. All that is awesome , but pair it with the tray design on top to catch the jewelry I would otherwise toss on the dresser in a hurry and it's just a fabulous design.
The leather exterior is beautiful. I wasn't sure about it not being wood, but the quality is fantastic and I'm so happy I took the chance and got it!!! Well worth the price and would make a great gift!
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Reviewed in the United States on October 16, 2025
★★★★★ 5
Beautiful box that spins
Very nice jewelry box with Spinny on the bottom, plenty of compartments for different options of different types of jewelry
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Reviewed in the United States on October 17, 2025
★★★★★ 5
So cutie
Color: Cloud White, Material Type: Paper, PU
This is a bit large for a travel size jewelry box lol I really thought it was going to be a bit smaller than what it was. I can see why some of the ladies in the comments are saying they’re using it as their main jewelry box since they don’t have much jewelry for a standard sized jewelry box.
With that being said, it’s cute and CAN be small enough for travel. It fits a lot and I got this one in particular bc I like that it has a bigger lower compartment for larger pieces. It’s a nice quality travel jewelry box. It’ll fit my needs. But if you have a knack for packing small and you value space. I’d say skip on this one or do due diligence to double check the measurements to see if it’s something you’re okay with packing.
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Reviewed in the United States on January 31, 2026
★★★★★ 5
Good value
Color: Jelly Pink, Material Type: Paper, PU
This is a great jewelry box for travel or to just keep at home. Very stylish and holds more than it looks like it would.
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Reviewed in the United States on February 10, 2026
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