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Description
GPC3/Glypican 3 His Tag Protein, MouseProduct Specification Species Mouse Synonyms GPC3, OCI5, Glypican 3, GTR2 2, MXR7, DGSX, SDYS Accession Q8CFZ4 Amino Acid Sequence Gln25 Met557, with C terminal 10*His
Product Specification
| Species | Mouse |
| Synonyms | GPC3, OCI5, Glypican-3, GTR2-2, MXR7, DGSX, SDYS |
| Accession | Q8CFZ4 |
| Amino Acid Sequence | Gln25-Met557, with C-terminal 10*His QPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGSDLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVRHAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYTQMMNPGLPESVLDINECLRGARRDLKVFGSFPKLIMTQVSKSLQVTRIFLQALNLGIEVINTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYILSLEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNGGKLTTTIGKLCAHSQQRQYRSAYYPEDLFIDKKILKVAHVEHEETLSSRRRELIQKLKSFINFYSALPGYICSHSPVAENDTLCWNGQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLRTMSVPKGKVLDKSLDEEGLESGDCGDDEDECIGSSGDGMVKVKNQLRFLAELAYDLDVDDAPGNKQHGNQKDNEITTSHSVGNMGGGSGGGSHHHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | 72-130kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference |
1、Kandil D H. et al. (2009) Glypican-3: a novel diagnostic marker for hepatocellular carcinoma and more. Adv Anat Pathol. 16(2): 125-129. 2、Maeda D. et al. (2009) Glypican-3 expression in clear cell adenocarcinoma of the ovary. Mod Pathol. 22(6): 824-832. |
Background
Glypican-3 (GPC3) belongs to a six-member family of membrane-bound heparan sulfate proteoglycans with a gene that is localized to Xq26.2. GPC3 belongs to a family of Glypicans are heparan sulfate proteoglycans that are bound to the cell surface by glycosyl phosphatidyli nositol. While six members of the glypican family are known in mammals, our study focused on glypican 3(GPC3). Loss-of-function mutations of GPC3 result in the Simpson- Golabi-Behmel syndrome, an X-linked disorder characterized by pre- and postnatal liver and other organ overgrowth. GPC3 is overexpressed in human hepatocellular carcinoma; however, its role in normal liver regeneration and hepatocyte proliferation is unknown. GPC3 is located on the X chromosome, and is highly expressed during embryogenesis and organogenesis. In the adult, on the other hand, GPC3 can only be detected in a limited number of tissues, including the lung, ovaries, mammary epithelium and mesothelium.
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4.8 ★★★★★
Based on 20 reviews
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Product Reviews
★★★★★ 3
My doggy no like!
Pattern Name: Star
My dog completely ignored them.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 3, 2026
★★★★★ 5
Fun toy
Pattern Name: Checkered
This was a very fun toy but didn't last too long with our 1-year-old lab who is an aggressive chewer.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 27, 2026
★★★★★ 5
Comfortable and convenient
They are awesome socks. Perfect for slides or flip flops. I used them traveling by plane. When you have to take your shoes off in security you can wear slip on shoes while still protecting your bare feet from the floors.
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Reviewed in the United States on September 22, 2022
★★★★★ 3
One pair too small
The two solid color pairs were good quality and fit well but the cute patterned ones didn’t have any stretch and were way too small to get on my feet. I was pretty bummed because they were the main reason I purchased this 3 pack.
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Reviewed in the United States on August 6, 2023
★★★★★ 5
Comfortable
I like these partial socks and how they keep my feet warm while I wear flip flops around the house I also use a pair to moisturize my heals at night
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 5, 2025
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