SKU: 79382839190

Rat Anti-Mouse CD170 Antibody (S-R691)

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Description

Rat Anti-Mouse CD170 Antibody (S-R691)Product Specification Host Rat Antigen CD170 Synonyms Sialic acid binding Ig like lectin 5; Siglec 5; Sialic acid binding Ig like lectin F (Siglec F; mSiglec F); Siglecf; Siglec5 Location Membrane Accession Q920G3 Clone Number S R691 Antibody Type Rat mAb Isotype IgG2b,k Application FCM Reactivity Ms Positive Sample C57BL 6 mouse bone marrow Purification Protein G Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer

Product Specification


Host Rat
Antigen CD170
Synonyms Sialic acid-binding Ig-like lectin 5; Siglec-5; Sialic acid-binding Ig-like lectin F (Siglec-F; mSiglec-F); Siglecf; Siglec5
Location Membrane
Accession Q920G3
Clone Number S-R691
Antibody Type Rat mAb
Isotype IgG2b,k
Application FCM
Reactivity Ms
Positive Sample C57BL/6 mouse bone marrow
Purification Protein G
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4
Stability & Storage 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution


application dilution species
FCM 1:2000 Ms

Background

CD170, also known as Siglec-5 or OBBP2, is a type I transmembrane glycoprotein and a member of the sialic acid-binding Ig-like lectin (Siglec) family. It is expressed on various immune cells, including monocytes, neutrophils, macrophages, and dendritic cells. This molecule is characterized by its ability to bind sialic acids, which are often found on the surface of cells. It contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic domain, which is involved in intracellular signaling and can inhibit the activation of immune cells. CD170 is involved in mediating sialic acid-dependent cell adhesion and plays a role in immune regulation. In addition, it has been implicated in immune evasion by certain pathogens, such as Group B Streptococcus.

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SKU: 79382839190

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4.9 ★★★★★
Based on 8 reviews
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M
Verified Purchase
MaryBeth K
Carnegie, US
★★★★★ 5
Fae Courts with High Intrigue
Format: Kindle
This book is one that just builds and builds and then surprises you to no end. You may think you know the villains and then you are jolted in another direction. Princess Reyna is a real gem, strong of character, a fierce fighter, and loyal to her family and kingdom. Just when you think she and Lorcan, well you know, the plot is flipped. Can't wait to see where this goes in book two.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on July 7, 2023
K
Verified Purchase
Kindle Customer Maureen
Dallas, US
★★★★★ 4
Slow, sorry but good
Format: Kindle
This was a slow moving book. Lots of character pov chapters, lots of superfluous descriptions and endless courtly appearances stalled this book to start. Once you get into the heart of the story, it takes off. Before you know it the book is done. My favorite character is Reyna. She is so strong. She is true to herself. She gets into a lot of trouble with her headstrong ways but it's entertaining. I have high hopes for Lorcan. He is honorable to a fault. Thane had turned out to be better than I thought but i still don't like him. Eislin is useless. Great plot twists at the end. I'm looking forward too book 2.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 6, 2020
F
Verified Purchase
Faifre6
Boise, US
★★★★★ 5
Very detailed! Beautiful world building! Strong Heroine!
Format: Kindle
Starts off a little slow and confusing with different POV’s, but starts to all come together towards the middle to make an elaborate plot line and makes it all worth it. Beautiful world building and attention to detail as well as great writing. The cliffhanger was gut wrenching! Can’t wait for the next book!
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Reviewed in the United States on March 4, 2020
I
Verified Purchase
Isabelle
Natrona Heights, US
★★★★★ 4
Interesting
Format: Kindle
This was a very captivating book once you got into it thoroughly. But the third person perspective was a bit hard to get used to. But as you got into it and followed the different characters, it was interesting and filled with intrigue, conflict and forbidden love. I can’t wait to read the next one and to complete the series.
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Reviewed in the United States on November 12, 2022
L
Verified Purchase
Lisa B.
Chelsea, US
★★★★★ 5
OUTSTANDING
Format: Kindle
This was very, very good. The world is vast and characters are complex. There is a good plot with a whole lot going on. This is well written. Good twists and turns and some heart breaking moments. You will love these characters, they have heart and loyalty. I am hoping that there will be several more books. We've yet to see anything from the Sea Court but only a mention of them here and there. The Wood Court was given a quick couple of scenes, and only as far as some warriors, we've yet to enter their court and the Shadow Court, I'm not sure if they will be a force for good or bad, but they definitely will play a much bigger role moving forward. This is primarily the Ice and Air Courts. Told in multiple views, which I loved, it gives you a chance to see things from different eyes. There's alot of political maneuvering and deception. I loved it and will pick up the next book as it becomes available. If you like The Fae and the courts, you should love this. I think the author has mucn in store for us.
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Reviewed in the United States on March 8, 2020

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