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Description
S-RMab® Cytokeratin 7 Recombinant Rabbit mAb (SDT-121-17)Product Specification Host Rabbit Antigen Cytokeratin 7 Synonyms Cytokeratin 7 (CK 7), Keratin 7 (K7), Sarcolectin, Type II keratin Kb7, KRT7 Immunogen Synthetic Peptide Location Cytoplasm Accession P08729 Clone Number SDT 121 17 Antibody Type Rabbit mAb Application WB, IHC P, ICC, FCM, IP, IF Reactivity Hu Purification Protein A Concentration 0. 5mg ml Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05%BSA, 0. 03% Proclin 300
Product Specification
| Host | Rabbit |
| Antigen | Cytokeratin 7 |
| Synonyms | Cytokeratin-7 (CK-7), Keratin-7 (K7), Sarcolectin, Type-II keratin Kb7, KRT7 |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm |
| Accession | P08729 |
| Clone Number | SDT-121-17 |
| Antibody Type | Rabbit mAb |
| Application | WB, IHC-P, ICC, FCM, IP, IF |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5mg/ml |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| IP | 1:25 | |
| ICC | 1:500 | |
| IHC-P | 1:500 | |
| FCM | 1:500 | |
| WB | 1:1000 | |
| IF | 1:200 |
Background
Cytokeratin 7 is the intermediate silk protein mainly expressed in epithelial cells. The heterodine of keratin consists of a polymerization filament by an acid -keratin (or type I keratin, keratin 9 to 23) and alkaline keratin (or type II keratin, keratin 1 to 8). Expression similar to but more limited than keratins 8 and 18 in simple, pseudostratified and ductal epithelium, mesothelium and urothelium.It's enerally expressed (with some variation) in adenocarcinoma of lung, breast, thyroid, endometrium, cervix, ovary, salivary gland, upper GI tract, urothelial carcinoma, papillary renal cell carcinoma and Paget disease It's generally negative (with some variation) in colorectal carcinoma, Merkel cell carcinoma, hepatocellular carcinoma, prostatic adenocarcinoma, adrenocortical tumors and squamous cell carcinoma.
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Exchange/Return Notes
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